Cisplatin (cisplatin) — Uses, Dosage, Side Effects & Safety

Drug class: Antineoplastic (Platinum-based Chemotherapy Agent)

Overview

Cisplatin is a chemotherapy medication used to treat various types of cancer, including testicular, ovarian, bladder, head and neck, lung, and cervical cancers . It works by interfering with the DNA in cancer cells, preventing them from multiplying and causing them to die. Cisplatin is usually given by intravenous (IV) infusion in a hospital or clinic setting under the supervision of a healthcare professional. It is often used in combination with other chemotherapy drugs for greater effectiveness. Key points for patients: Cisplatin can cause significant side effects, including nausea, vomiting, kidney problems, and hearing loss. Your doctor will monitor you closely and may prescribe medications to help manage side effects. Staying well-hydrated and reporting any unusual symptoms promptly is important during treatment.

Therapeutic uses

• Cancer
• Malignancies

Common side effects

• Nausea and vomiting
• Kidney damage (nephrotoxicity)
• Hearing loss (ototoxicity)
• Bone marrow suppression (myelosuppression)
• Peripheral neuropathy
• Electrolyte disturbances
• Anaphylactic-like reactions

Frequently Asked Questions about Cisplatin

What types of cancer is cisplatin used to treat?

Cisplatin is used to treat testicular, ovarian, bladder, head and neck, lung, and cervical cancers, among others.

How is cisplatin given?

Cisplatin is administered as an intravenous (IV) infusion in a hospital or clinic, usually over several hours.

What are the most serious side effects of cisplatin?

Serious side effects include kidney damage, hearing loss, severe nausea/vomiting, nerve damage, and bone marrow suppression.

Can cisplatin cause hearing loss?

Yes, cisplatin can cause permanent hearing loss, especially in children and at higher doses. Hearing should be monitored during treatment.

Is cisplatin safe during pregnancy?

Cisplatin is not recommended during pregnancy as it can harm the unborn baby. Effective contraception should be used.

What should I do if I miss a dose?

Contact your healthcare provider immediately if you miss a scheduled dose. Do not try to make up the dose yourself.

Are there any foods or medicines I should avoid while on cisplatin?

Avoid nephrotoxic and ototoxic drugs unless approved by your doctor, and avoid live vaccines. Stay hydrated and follow your healthcare provider's instructions.

Educational information only. Always consult a qualified healthcare professional before starting, stopping, or changing any medication.