Dapagliflozin (dapagliflozin) — Uses, Dosage, Side Effects & Safety
Drug class: SGLT2 inhibitor
Overview
Dapagliflozin is a prescription medicine used to help lower blood sugar (glucose) in adults with type 2 diabetes. It is also approved to reduce the risk of hospitalization for heart failure and to treat chronic kidney disease in certain patients. Dapagliflozin works by helping your kidneys remove excess sugar from your body through urine. It belongs to a group of medicines called SGLT2 inhibitors, which block a protein in the kidneys responsible for reabsorbing glucose back into the blood. Key points for patients: Dapagliflozin is not for type 1 diabetes or diabetic ketoacidosis. It is usually taken once daily, with or without food. Regular monitoring of blood sugar and kidney function is important while using this medicine.
Therapeutic uses
- Type 2 Diabetes Mellitus
- Heart Failure
Common side effects
- Genital yeast infections
- Urinary tract infections
- Increased urination
- Ketoacidosis
- Dehydration
- Kidney problems
- Fournier's gangrene
Frequently Asked Questions about Dapagliflozin
What is dapagliflozin used for?
Dapagliflozin is used to lower blood sugar in adults with type 2 diabetes, reduce the risk of hospitalization for heart failure, and treat chronic kidney disease in certain patients.
How does dapagliflozin work?
It works by blocking a protein in the kidneys (SGLT2), causing excess glucose to be removed from the body in the urine.
Can dapagliflozin cause low blood sugar?
Dapagliflozin alone rarely causes low blood sugar, but the risk increases if used with insulin or other diabetes medicines.
Is dapagliflozin safe in pregnancy or breastfeeding?
Dapagliflozin is not recommended during pregnancy or breastfeeding due to potential risks to the baby. Discuss alternatives with your doctor.
What should I do if I develop signs of infection while taking dapagliflozin?
Contact your doctor promptly if you notice symptoms of urinary tract or genital infection, such as pain, burning, unusual discharge, or fever.
Can dapagliflozin be used in patients with kidney problems?
Dapagliflozin should not be used in patients with severe kidney impairment or on dialysis. Dose adjustments may be needed for moderate kidney disease.
What are the serious risks of dapagliflozin?
Serious risks include ketoacidosis, severe infections (including Fournier’s gangrene), dehydration, and kidney problems. Seek immediate medical attention if you experience symptoms of these conditions.
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Educational information only. Always consult a qualified healthcare professional before starting, stopping, or changing any medication.