Eliquis (apixaban) (apixaban) — Uses, Dosage, Side Effects & Safety

Drug class: Direct oral anticoagulant (DOAC); Factor Xa inhibitor

Overview

Eliquis (apixaban) is a prescription medication used to reduce the risk of blood clots and stroke in people with certain heart and blood vessel conditions, such as atrial fibrillation (not caused by a heart valve problem), deep vein thrombosis (DVT), and pulmonary embolism (PE). It is also used to prevent DVT, which can lead to PE, in people who have had hip or knee replacement surgery. Eliquis works by blocking a specific clotting factor in the blood called Factor Xa. By inhibiting this factor, Eliquis helps prevent the formation of harmful blood clots without affecting existing clots. This makes it an effective alternative to older blood thinners like warfarin, often requiring less frequent monitoring. Key points for patients: Take Eliquis exactly as prescribed, at the same times each day. Do not stop taking it without consulting your doctor, as stopping suddenly may increase your risk of a serious blood clot or stroke. Always inform your healthcare provider about all medications and supplements you are taking.

Therapeutic uses

• Atrial fibrillation
• Venous thromboembolism

Common side effects

• Bleeding (e.g., nosebleeds, gum bleeding, bruising)
• Nausea
• Anemia
• Rash
• Major bleeding (e.g., gastrointestinal, intracranial)
• Spinal/epidural hematoma
• Allergic reactions (e.g., swelling, difficulty breathing)

Frequently Asked Questions about Eliquis (apixaban)

What is Eliquis used for?

Eliquis is used to prevent stroke and blood clots in people with nonvalvular atrial fibrillation, treat and prevent deep vein thrombosis (DVT) and pulmonary embolism (PE), and reduce the risk of DVT after hip or knee replacement surgery.

How does Eliquis work?

Eliquis works by blocking Factor Xa, an important protein in the blood clotting process. This helps prevent the formation of harmful blood clots.

Can I stop taking Eliquis suddenly?

No. Stopping Eliquis suddenly can increase your risk of developing a blood clot or stroke. Always consult your doctor before making any changes to your medication.

What should I do if I miss a dose?

Take the missed dose as soon as you remember on the same day. Do not double up on doses. Resume your regular schedule the next day.

Are there foods or drinks I should avoid while taking Eliquis?

Unlike warfarin, Eliquis does not have significant food interactions. However, avoid excessive alcohol and discuss any herbal supplements with your doctor.

Is Eliquis safe during pregnancy or breastfeeding?

Eliquis is not recommended during pregnancy or breastfeeding unless specifically prescribed by your doctor, as its safety has not been established in these populations.

What are the signs of serious bleeding while on Eliquis?

Signs include prolonged or unusual bleeding, blood in urine or stools, severe headache, dizziness, or coughing/vomiting blood. Seek immediate medical attention if these occur.

Educational information only. Always consult a qualified healthcare professional before starting, stopping, or changing any medication.