Goserelin (goserelin) — Uses, Dosage, Side Effects & Safety

Drug class: Gonadotropin-Releasing Hormone (GnRH) Agonist

Overview

Goserelin is a medication used to treat certain hormone-sensitive cancers, such as prostate cancer in men and breast cancer in premenopausal women. It is also prescribed for endometriosis and to thin the lining of the uterus before certain surgical procedures. Goserelin works by reducing the amount of sex hormones (testosterone in men and estrogen in women) produced by the body. It does this by acting on the pituitary gland, leading to a temporary decrease in hormone levels. This helps slow or stop the growth of hormone-dependent tumors and reduces symptoms associated with these conditions. Key points for patients: Goserelin is given as a small implant injected under the skin, usually in the abdomen. It is important to attend all scheduled appointments for injections and to discuss any side effects or concerns with your healthcare provider.

Therapeutic uses

• Prostate cancer
• Breast cancer (pre/perimenopausal)
• Endometriosis
• Uterine fibroids
• Central precocious puberty

Common side effects

• Hot flashes
• Decreased libido
• Erectile dysfunction (men)
• Vaginal dryness (women)
• Headache
• Mood changes
• Bone pain
• Injection site reactions

Frequently Asked Questions about Goserelin

What is goserelin used for?

Goserelin is used to treat hormone-sensitive prostate cancer, breast cancer in premenopausal women, endometriosis, and to thin the uterine lining before surgery.

How is goserelin administered?

Goserelin is given as a small implant injected under the skin of the abdomen by a healthcare professional, typically every 28 days or every 12 weeks depending on the dose.

What are the most common side effects?

Common side effects include hot flashes, decreased libido, mood changes, sweating, and injection site reactions.

Can goserelin be used during pregnancy?

No, goserelin should not be used during pregnancy as it may harm the unborn baby. Effective contraception is recommended during treatment.

Does goserelin affect bone health?

Yes, long-term use of goserelin can decrease bone mineral density, increasing the risk of osteoporosis. Your doctor may monitor your bone health during treatment.

What should I do if I miss a dose?

Contact your healthcare provider as soon as possible to reschedule your injection. Do not attempt to administer the medication yourself.

Are there any serious risks with goserelin?

Serious risks include allergic reactions, increased risk of diabetes, cardiovascular events, and spinal cord compression in patients with metastatic cancer.

Educational information only. Always consult a qualified healthcare professional before starting, stopping, or changing any medication.