Januvia XR (sitagliptin extended-release) — Uses, Dosage, Side Effects & Safety

Drug class: Endocrine & Metabolic Disorders

Overview

Januvia XR is an oral prescription medication used to help control blood sugar levels in adults with type 2 diabetes mellitus. It is not used for type 1 diabetes or diabetic ketoacidosis. Januvia XR is typically used along with diet and exercise, and sometimes in combination with other diabetes medications. Januvia XR contains sitagliptin in an extended-release formulation. It works by increasing the levels of natural substances called incretins, which help to control blood sugar by increasing insulin release and decreasing the amount of sugar made by the liver. Key points for patients: Januvia XR is usually taken once daily, with or without food. It is important to follow your healthcare provider’s instructions and continue regular blood sugar monitoring. This medication is not a substitute for healthy lifestyle changes.

Therapeutic uses

  • Type 2 Diabetes Mellitus
  • Glycemic control
  • Reduction of HbA1c levels
  • Adjunct to diet and exercise

Common side effects

  • Hypoglycemia
  • Nausea
  • Diarrhea
  • Upper respiratory tract infection
  • Headache
  • Pancreatitis
  • Severe allergic reactions

Frequently Asked Questions about Januvia XR

What is Januvia XR used for?

Januvia XR is used to help control blood sugar levels in adults with type 2 diabetes, usually in combination with diet and exercise.

How does Januvia XR work?

Januvia XR increases incretin levels, which help the body release more insulin after meals and reduce the amount of sugar produced by the liver.

Can Januvia XR cause low blood sugar?

Januvia XR alone has a low risk of causing hypoglycemia, but the risk increases when used with insulin or sulfonylureas.

What should I do if I miss a dose?

Take the missed dose as soon as you remember, unless it is almost time for your next dose. Do not double up doses.

Is Januvia XR safe in pregnancy or breastfeeding?

There is limited data on the use of Januvia XR in pregnancy or breastfeeding. Discuss with your doctor before use.

Can I take Januvia XR with other diabetes medications?

Januvia XR can be used with other diabetes medications, but your doctor may need to adjust your doses to prevent low blood sugar.

What are the signs of a serious allergic reaction to Januvia XR?

Signs include rash, itching, swelling (especially of the face/tongue/throat), severe dizziness, and trouble breathing. Seek emergency help if these occur.

Related Januvia XR information

Educational information only. Always consult a qualified healthcare professional before starting, stopping, or changing any medication.