Trastuzumab (trastuzumab) — Uses, Dosage, Side Effects & Safety

Drug class: Monoclonal antibody, Antineoplastic agent

Overview

Trastuzumab is a prescription medicine used to treat certain types of breast cancer and stomach cancer that overexpress the HER2 protein. It is most commonly used in HER2-positive breast cancer, either alone or in combination with other chemotherapy medicines. Trastuzumab works by targeting the HER2 receptor, a protein found in high amounts on some cancer cells. By binding to this receptor, trastuzumab helps slow or stop the growth of cancer cells and may also help the immune system destroy them. Key points for patients: Trastuzumab is given as an infusion into a vein or as a subcutaneous injection, usually in a hospital or clinic. It is important to attend all scheduled appointments and report any side effects, especially heart problems or allergic reactions, to your healthcare provider.

Frequently Asked Questions about Trastuzumab

What is trastuzumab used for?

Trastuzumab is used to treat HER2-positive breast cancer and HER2-positive metastatic gastric or gastroesophageal junction cancer.

How does trastuzumab work?

It targets the HER2 receptor on cancer cells, blocking their growth and helping the immune system destroy them.

What are the most serious side effects of trastuzumab?

The most serious side effects include heart failure, severe allergic reactions, and lung problems.

Can I take trastuzumab if I am pregnant or breastfeeding?

No. Trastuzumab can harm an unborn baby and should not be used during pregnancy or breastfeeding.

How is trastuzumab given?

It is given as an intravenous infusion or subcutaneous injection by a healthcare professional in a clinic or hospital.

Do I need regular tests while on trastuzumab?

Yes. Your doctor will monitor your heart function and other health parameters regularly during treatment.

What should I do if I miss a dose?

Contact your healthcare provider as soon as possible to reschedule your missed dose. Do not self-administer.

Educational information only. Always consult a qualified healthcare professional before starting, stopping, or changing any medication.