Tresiba (insulin degludec) (insulin degludec) — Uses, Dosage, Side Effects & Safety

Drug class: Long-acting basal insulin analogue

Overview

Tresiba (insulin degludec) is a long-acting insulin used to help control blood sugar levels in people with diabetes mellitus, including both type 1 and type 2 diabetes. It is typically injected once daily and provides a steady, consistent release of insulin over 24 hours or longer. Insulin degludec works by replacing the insulin that your body is unable to produce or use effectively. This helps move sugar from the blood into the cells, where it can be used for energy. Keeping blood sugar within a target range helps prevent complications of diabetes, such as kidney damage, nerve problems, and vision loss. Patients should know that Tresiba is not a cure for diabetes but is an important part of a comprehensive diabetes management plan that includes diet, exercise, and regular blood glucose monitoring. Always use Tresiba exactly as prescribed and do not share your injection device with others.

Therapeutic uses

  • Type 1 diabetes mellitus
  • Type 2 diabetes mellitus

Common side effects

  • Hypoglycemia
  • Injection site reactions
  • Allergic reactions
  • Lipodystrophy
  • Weight gain
  • Peripheral edema
  • Hypokalemia

Frequently Asked Questions about Tresiba (insulin degludec)

How long does Tresiba last in the body?

Tresiba has an ultra-long duration of action, lasting at least 42 hours, which allows for once-daily dosing and flexibility in injection timing.

Can Tresiba be mixed with other insulins?

Tresiba should not be mixed with other insulins or solutions. It must be administered as a separate injection.

What should I do if I experience low blood sugar while using Tresiba?

Treat low blood sugar immediately with a fast-acting carbohydrate (such as glucose tablets or juice). Monitor your blood sugar and seek medical help if symptoms are severe or do not improve.

Is Tresiba safe during pregnancy and breastfeeding?

Tresiba may be used during pregnancy and breastfeeding if clearly needed. Insulin requirements may change during these periods, so close monitoring by your healthcare provider is essential.

How should I store Tresiba pens or cartridges?

Store unopened pens/cartridges in the refrigerator. Once in use, keep at room temperature and use within 8 weeks. Do not freeze or expose to excessive heat.

What are the signs of an allergic reaction to Tresiba?

Signs include rash, itching, swelling, severe dizziness, or difficulty breathing. Seek emergency medical attention if these occur.

Can children use Tresiba?

Yes, Tresiba is approved for use in children aged 1 year and older. Dosing and monitoring should be managed by a pediatric diabetes specialist.

Educational information only. Always consult a qualified healthcare professional before starting, stopping, or changing any medication.