Iloprost — Uses, Dosage, Side Effects & Safety

Drug class: Cardiovascular & Circulatory System

Overview

Iloprost is a medication used to treat pulmonary arterial hypertension (PAH), a condition where high blood pressure in the lungs makes it harder for the heart to pump blood through the lungs. It is also used in some countries for the treatment of severe peripheral arterial disease and Raynaud's phenomenon when other treatments have failed. Iloprost works by mimicking the effects of prostacyclin, a natural substance in the body that widens (dilates) blood vessels and prevents blood clots. By relaxing the blood vessels in the lungs, iloprost helps lower blood pressure in the lungs and improves the ability to exercise. Key points for patients: Iloprost is usually inhaled using a special nebulizer device several times a day. It is important to use it exactly as prescribed and not to skip doses. Some people may experience side effects like flushing, headache, or cough. Always inform your doctor about any other medications you are taking.

Therapeutic uses

• Pulmonary arterial hypertension (PAH)
• Critical limb ischemia (CLI)
• Raynaud's phenomenon (severe)
• Thromboangiitis obliterans (Buerger's disease)

Common side effects

• Headache
• Flushing
• Nausea
• Jaw pain
• Hypotension
• Dizziness
• Palpitations
• Chest pain

Frequently Asked Questions about Iloprost

What is iloprost used for?

Iloprost is primarily used to treat pulmonary arterial hypertension (PAH) and, in some regions, severe peripheral arterial disease and Raynaud's phenomenon.

How does iloprost work?

Iloprost works by relaxing and widening blood vessels, reducing blood pressure in the lungs and improving blood flow.

How is iloprost administered?

Iloprost is usually inhaled using a nebulizer device several times a day. It may also be given as an intravenous infusion in hospital settings.

What are the most common side effects?

Common side effects include flushing, headache, cough, jaw pain, nausea, and dizziness.

Can iloprost be used during pregnancy?

Iloprost should only be used during pregnancy if clearly needed and prescribed by your doctor. Discuss risks and benefits with your healthcare provider.

What should I do if I miss a dose?

Take the missed dose as soon as you remember unless it is almost time for your next scheduled dose. Do not double up doses.

Are there any foods or drugs to avoid while taking iloprost?

Avoid alcohol and inform your doctor about all medications, especially blood thinners and other vasodilators, as interactions may occur.

Educational information only. Always consult a qualified healthcare professional before starting, stopping, or changing any medication.