Keytruda (pembrolizumab) (pembrolizumab) — Uses, Dosage, Side Effects & Safety

Drug class: Immune Checkpoint Inhibitor (Anti-PD-1 Monoclonal Antibody)

Overview

Keytruda (pembrolizumab) is a prescription medicine used to treat various types of cancer, including melanoma, non-small cell lung cancer, head and neck cancer, classical Hodgkin lymphoma, urothelial carcinoma, and several others. It is often used when cancer has spread or returned after other treatments. Keytruda works by helping your immune system recognize and attack cancer cells. It blocks a protein called PD-1 on immune cells, which normally prevents them from attacking healthy cells. By blocking PD-1, Keytruda allows immune cells to target and destroy cancer cells more effectively. Patients should know that Keytruda is given as an intravenous (IV) infusion in a healthcare setting, usually every 3 or 6 weeks. It can cause side effects, some of which may be serious. Regular monitoring by your healthcare team is important during treatment.

Therapeutic uses

• Melanoma
• Non-small cell lung cancer (NSCLC)
• Head and neck squamous cell carcinoma (HNSCC)
• Classical Hodgkin lymphoma (cHL)
• Urothelial carcinoma

Common side effects

• Fatigue
• Nausea
• Diarrhea
• Rash
• Pneumonitis
• Colitis
• Hepatitis
• Endocrinopathies

Frequently Asked Questions about Keytruda (pembrolizumab)

What types of cancer does Keytruda treat?

Keytruda is approved for several cancers, including melanoma, non-small cell lung cancer, head and neck squamous cell carcinoma, classical Hodgkin lymphoma, urothelial carcinoma, and others. Your doctor will determine if it is suitable for your specific cancer type.

How is Keytruda administered?

Keytruda is given as an intravenous (IV) infusion in a hospital or clinic, usually every 3 or 6 weeks, depending on your treatment plan.

What are the most common side effects?

The most common side effects include fatigue, nausea, rash, itching, diarrhea, decreased appetite, and joint pain.

Can I receive vaccines while on Keytruda?

You should avoid live vaccines during treatment with Keytruda. Inactivated vaccines may be used, but always consult your doctor first.

Is Keytruda safe during pregnancy or breastfeeding?

Keytruda may harm an unborn baby and is not recommended during pregnancy or breastfeeding. Use effective contraception during treatment and for at least 4 months after the last dose.

What should I do if I miss a dose?

Contact your healthcare provider as soon as possible to reschedule your missed infusion. Do not try to make up the dose yourself.

How long does treatment with Keytruda last?

Treatment duration varies based on cancer type, response to therapy, and side effects. Your doctor will determine the best length of treatment for you.

Educational information only. Always consult a qualified healthcare professional before starting, stopping, or changing any medication.