Nivolumab (nivolumab) — Uses, Dosage, Side Effects & Safety

Drug class: Immune Checkpoint Inhibitor (Anti-PD-1 Monoclonal Antibody)

Overview

Nivolumab is a prescription medicine used to treat several types of cancer, including melanoma, non-small cell lung cancer, renal cell carcinoma, classical Hodgkin lymphoma, head and neck squamous cell carcinoma, urothelial carcinoma, and others. It works by helping your immune system recognize and attack cancer cells more effectively. Nivolumab belongs to a group of medicines called immune checkpoint inhibitors. It blocks a protein called PD-1 on immune cells, which normally helps keep the immune system from attacking normal cells. By blocking PD-1, nivolumab allows immune cells to better target and destroy cancer cells. Key points for patients: Nivolumab is given as an intravenous infusion in a hospital or clinic. It can cause side effects related to increased immune activity, so regular monitoring is important. Always report new symptoms to your healthcare provider promptly.

Frequently Asked Questions about Nivolumab

What types of cancer does nivolumab treat?

Nivolumab is approved for melanoma, non-small cell lung cancer, renal cell carcinoma, classical Hodgkin lymphoma, head and neck squamous cell carcinoma, urothelial carcinoma, and some other cancers.

How is nivolumab administered?

It is given as an intravenous infusion by a healthcare professional, typically every 2 or 4 weeks depending on your treatment plan.

What are the most common side effects?

Fatigue, rash, itching, nausea, decreased appetite, cough, and mild diarrhea are the most common side effects.

Can nivolumab cause serious side effects?

Yes, nivolumab can cause severe immune-related side effects affecting organs such as the lungs, liver, intestines, kidneys, skin, and hormone glands. Prompt reporting of symptoms is important.

Is nivolumab safe during pregnancy or breastfeeding?

Nivolumab is not recommended during pregnancy or breastfeeding due to potential risks to the baby.

What should I do if I miss a dose?

Contact your healthcare provider to reschedule as soon as possible. Do not try to self-administer or double up doses.

Are there any medicines or vaccines I should avoid?

Avoid live vaccines and discuss all medicines and supplements with your doctor before starting nivolumab.

Educational information only. Always consult a qualified healthcare professional before starting, stopping, or changing any medication.