Pazopani (pazopanib) — Uses, Dosage, Side Effects & Safety

Drug class: Tyrosine kinase inhibitor (TKI); Antineoplastic agent

Overview

Pazopani (pazopanib) is a prescription medication used to treat certain types of cancer, including advanced renal cell carcinoma (kidney cancer) and advanced soft tissue sarcoma in adults who have already received chemotherapy. It works by blocking specific proteins called tyrosine kinases, which are involved in the growth of cancer cells and the formation of new blood vessels that supply tumors. By interfering with these proteins, Pazopani helps slow or stop the growth and spread of cancer. Patients should be aware that regular blood tests are needed to monitor for side effects, and the medication should be taken exactly as prescribed. It is important to inform your healthcare provider about all other medicines you are taking, as Pazopani can interact with many drugs.

Therapeutic uses

• Advanced renal cell carcinoma (RCC)
• Advanced soft tissue sarcoma (STS)
• Ovarian cancer (recurrent epithelial ovarian, fallopian tube, or primary peritoneal cancer)

Common side effects

• Diarrhea
• Nausea
• Vomiting
• Fatigue
• Hypertension
• Hair color changes
• Liver enzyme elevations
• Thrombotic microangiopathy

Frequently Asked Questions about Pazopani

What is Pazopani used for?

Pazopani is used to treat advanced kidney cancer (renal cell carcinoma) and advanced soft tissue sarcoma in adults who have received prior chemotherapy.

How should I take Pazopani?

Take Pazopani on an empty stomach, at least 1 hour before or 2 hours after a meal, with a full glass of water. Swallow the tablet whole.

What are the most common side effects?

Common side effects include diarrhea, high blood pressure, hair color changes, nausea, vomiting, loss of appetite, and fatigue.

Can I take Pazopani with other medications?

Pazopani can interact with many other medications. Always inform your doctor or pharmacist about all medicines and supplements you are taking.

What should I do if I miss a dose?

If you miss a dose, take it as soon as you remember unless it is less than 12 hours until your next dose. Do not double up doses.

Is Pazopani safe during pregnancy or breastfeeding?

Pazopani is not recommended during pregnancy or breastfeeding due to potential harm to the baby.

How will my doctor monitor my treatment?

Your doctor will order regular blood tests to check your liver function, blood pressure, and other parameters to ensure safe and effective treatment.

Educational information only. Always consult a qualified healthcare professional before starting, stopping, or changing any medication.