Kevzara (Sarilumab) (Sarilumab) — Uses, Dosage, Side Effects & Safety

Drug class: Autoimmune & Immunological

Overview

Kevzara (sarilumab) is a prescription medicine used to treat adults with moderate to severe rheumatoid arthritis (RA) who have not responded well to, or cannot tolerate, one or more disease-modifying antirheumatic drugs (DMARDs) such as methotrexate. It works by blocking the activity of interleukin-6 (IL-6), a substance in the body that causes inflammation and plays a key role in autoimmune diseases like RA. By reducing inflammation, Kevzara helps decrease joint pain, swelling, and stiffness, and may slow down joint damage. It is given as a subcutaneous injection, usually every two weeks. Patients should be aware that Kevzara can affect the immune system, increasing the risk of infections, and regular blood tests are needed to monitor for side effects.

Therapeutic uses

  • Rheumatoid Arthritis

Common side effects

  • Injection site reactions
  • Upper respiratory tract infections
  • Urinary tract infections
  • Neutropenia
  • Increased liver enzymes
  • Serious infections (e.g., pneumonia, cellulitis)
  • Gastrointestinal perforation

Frequently Asked Questions about Kevzara (Sarilumab)

What is Kevzara used for?

Kevzara is used to treat moderate to severe rheumatoid arthritis in adults who have not responded well to other DMARDs.

How does Kevzara work?

Kevzara blocks the interleukin-6 (IL-6) receptor, reducing inflammation and immune system activity that contribute to rheumatoid arthritis.

Can I take Kevzara if I have an infection?

No, you should not start Kevzara if you have an active infection. Tell your doctor about any signs of infection before and during treatment.

How is Kevzara administered?

Kevzara is given as a subcutaneous injection, usually every two weeks, into the thigh, abdomen, or upper arm.

What should I do if I miss a dose?

Inject the missed dose as soon as you remember, unless it is almost time for your next dose. Do not double up doses.

Are there any foods or medicines I should avoid while taking Kevzara?

Avoid live vaccines and inform your doctor about all other medications, especially other immunosuppressants.

Is Kevzara safe during pregnancy or breastfeeding?

The safety of Kevzara in pregnancy or breastfeeding is not established. Discuss risks and benefits with your healthcare provider.

Related Kevzara (Sarilumab) information

Educational information only. Always consult a qualified healthcare professional before starting, stopping, or changing any medication.