Skyrizi (Risankizumab) — Uses, Dosage, Side Effects & Safety

Drug class: Autoimmune & Immunological

Overview

Skyrizi (risankizumab) is an advanced biologic medication for moderate to severe plaque psoriasis, psoriatic arthritis, and Crohns disease. It specifically targets IL-23, a key driver of inflammation.

Therapeutic uses

• Moderate to severe plaque psoriasis
• Psoriatic arthritis
• Moderate to severe Crohns disease

Common side effects

• Upper respiratory infections
• Headache
• Fatigue
• Injection site reactions
• Tinea infections

Drug interactions

• Live vaccines
• CYP450 substrates (monitor)

Contraindications

• Serious active infection
• Live vaccine administration

How to use Skyrizi

For psoriasis: 150mg at weeks 0, 4, and then every 12 weeks. For Crohns: IV induction followed by subcutaneous maintenance. Self-injection possible after training.

Precautions & warnings

Monitor for infections, especially fungal infections. Avoid live vaccines. Complete age-appropriate vaccinations before starting. Report signs of infection immediately.

Frequently Asked Questions about Skyrizi

What is Skyrizi used for?

Skyrizi is used as prescribed by healthcare professionals. Follow your doctor's instructions for proper use and dosing.

How should I take Skyrizi?

Take Skyrizi exactly as prescribed by your doctor. Read the medication guide and follow all instructions on the prescription label.

What are the side effects of Skyrizi?

Skyrizi may cause side effects. Contact your healthcare provider if you experience any unusual symptoms or side effects.

Can I stop taking Skyrizi suddenly?

Do not stop taking Skyrizi suddenly without consulting your doctor. Sudden discontinuation may cause withdrawal symptoms.

How long does it take for Skyrizi to work?

The time it takes for Skyrizi to work varies. Some effects may be seen within hours or days, while full benefits may take weeks. Continue as prescribed.

Is Skyrizi safe during pregnancy?

Consult your healthcare provider about using Skyrizi during pregnancy or breastfeeding. They will weigh the benefits and risks.

What should I avoid while taking Skyrizi?

Follow your doctor's advice about activities, foods, or other medications to avoid while taking Skyrizi. Read the medication guide carefully.

What happens if I miss a dose of Skyrizi?

If you miss a dose of Skyrizi, take it as soon as you remember. If it's almost time for your next dose, skip the missed dose.

Educational information only. Always consult a qualified healthcare professional before starting, stopping, or changing any medication.